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1 article(s) from Biermann, Friederike

Navigating and expanding the roadmap of natural product genome mining tools

Friederike Biermann,
Sebastian L. Wenski and
Eric J. N. Helfrich

Beilstein J. Org. Chem. 2022, 18, 1656–1671, doi:10.3762/bjoc.18.178

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Graphical Abstract

Figure 1: Examples of prominent natural products: N-butyrylhomoserine lactone (1), pyoverdin (2), malleicypro...

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Figure 2: Biosynthetic principles of (A) assembly line-like pathways and (B) discrete multi-enzymatic assembl...

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Figure 3: Universal (A, B, F) NP class and NP family-specific (C, D, F) signature sequences in NP BGCs and se...

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Figure 4: Concepts of algorithms in order of complexity and examples of genome mining tools that employ the r...

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Figure 5: Examples of peptide NPs, the corresponding BGCs of which were determined through retrobiosynthetic ...

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Figure 6: gcBGC prioritization process. The bar represents all identified gene clusters in one organism and i...

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Figure 7: Genome alignments of related organisms revealing the presence of syntenic (purple) as well as non-s...

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Published 06 Dec 2022

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